Marion ClaverieAssociate professor (Chair E2S UPPA - MANTA)
- IPREM
2 av. P. Angot64000 Pau - Enzymology, bio-materials, biopolymers, marine ressources
- marion.claverie @ univ-pau.fr
Education
Education
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2017: PhD of Toulouse University in Biochemistry (Enzyme catalysis and molecular engineering). Supervisor: Pr. Magali Remaud-Simeon
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2009-2013: Engineering degree INSA Toulouse (Institut National des Sciences Appliquées) - Specialty: Biochemistry - Synthetic Biology
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2012: Erasmus student at University of Nottingham (England)
Experience
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2018 - Post Doctoral fellow - Laboratoire d’Ingénierie des Systèmes Biologiques et des Procédés, (LISBP) Toulouse – CIMES and RMN Teams. Development of isotopic labelling to study structure/function relationships of GH70 enzymes.
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2013-2017 - PhD student - LISBP Toulouse - CIMES Team. GH-70 dextransucrases: Insights on the molecular determinants of dextran molar mass control.
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2013 - Research Internship - 6 months -LISBP Toulouse - CIMES Team. Biochemical characterization of two new glucansucrases with original properties.
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2012 - Research & Development Internship - 4 months -Fromagerie des Chaumes, groupe Bongrain SA, Jurançon. Study of Microorganism/Environment interactions and analysis of oxygen consumption by the microbial flora of cheeses.
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2011 - Research & Development Internship - 2 months - Abengoa Bioenergy France (bioethanol factory), Arance. Optimization of yeast propagation before the fermentation steps using experimental design.
Skills
Molecular Biology
Cloning, design with in silico tools, site-directed and random mutagenesis.
Biocatalysis
Recombinant protein expression by fermentation. Purification (batch and AKTA), screening, biochemical and structural characterization of proteins. Enzymatic assays, enzymatic reaction optimization. Enzymatic synthesis and physico-chemical analyses of biopolymers.
Biophysics
Crystallogenesis, Crystallography, SAXS, protein-ligand interaction analyses, uniform and specific isotopic labelling.
Analytical techniques
HPLC, HPAEC-PAD, HPSEC.
Research interests
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Structure/function relationships study of Glycoside Hydrolase enzymes
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Development of marine-based biomaterials
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Valorization of marine resources and by-products
Supervision
People management
- Supervision of two Bachelor students and two Master students.
Teaching
Institut National des Sciences Appliquées (INSA), Toulouse. Lab courses for 1st to 5th year students:
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Solution Chemistry
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Molecular biology
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Microbiology
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Biocatalysis
Projects
From 2019: Postdoctoral fellowship within the Partenarial Chair E2S UPPA – MANTA https://e2s-uppa.eu/en/research/chairs-of-excellence/manta-marine-materials.html
Funded by E2S UPPA, Communauté d’Agglomération Pays Basque, Région Nouvelle Aquitaine, Comité Interdépartemental des Pêches Maritimes et des Elevages Marins, Laboratoire de Biarritz and Lees for 5 years at UPPA, France