Marion ClaveriePhD and Engineer in Biochemistry
- Post Doctoral Fellow (Associate professor) Chair E2S UPPA - MANTA (IPREM - Université de Pau & Pays Adour, France)
IPREM - UMR 5254 UPPA/CNRS
Technopole Helioparc - 2, av. Pdt P. Angot - 64 053 PAU cedex 09Enzymologie, bio-matériaux, bio-polymères, ressources marines
marion.claverie @ univ-pau.fr
Parcours
Academic Education
2017: PhD of Toulouse University in Biochemistry (Enzyme catalysis and molecular engineering). Supervisor: Pr. Magali Remaud-Simeon
2009-2013: Engineering degree INSA Toulouse (Institut National des Sciences Appliquées) - Specialty: Biochemistry - Synthetic Biology
2012: Erasmus student at University of Nottingham (England)
Academic Positions
2018 - Post Doctoral fellow - Laboratoire d’Ingénierie des Systèmes Biologiques et des Procédés, (LISBP) Toulouse – CIMES and RMN Teams
Development of isotopic labelling to study structure/function relationships of GH70 enzymes.
2013-2017 - PhD student - LISBP Toulouse - CIMES Team
GH-70 dextransucrases: Insights on the molecular determinants of dextran molar mass control.
2013 - Research Internship - 6 months -LISBP Toulouse - CIMES Team
Biochemical characterization of two new glucansucrases with original properties.
Positions in Industry
2012 - Research & Development Internship - 4 months -Fromagerie des Chaumes, groupe Bongrain SA, Jurançon
Study of Microorganism/Environment interactions and analysis of oxygen consumption by the microbial flora of cheeses.
2011 - Research & Development Internship - 2 months - Abengoa Bioenergy France (bioethanol factory), Arance
Optimization of yeast propagation before the fermentation steps using experimental design.
Compétences
Molecular Biology
Cloning, design with in silico tools, site-directed and random mutagenesis.
Biocatalysis
Recombinant protein expression by fermentation. Purification (batch and AKTA), screening, biochemical and structural characterization of proteins. Enzymatic assays, enzymatic reaction optimization. Enzymatic synthesis and physico-chemical analyses of biopolymers.
Biophysics
Crystallogenesis, Crystallography, SAXS, protein-ligand interaction analyses, uniform and specific isotopic labelling.
Analytical techniques
HPLC, HPAEC-PAD, HPSEC.
Thèmes de recherche
-
Structure/function relationships study of Glycoside Hydrolase enzymes
-
Development of marine-based biomaterials
-
Valorization of marine resources and by-products
Encadrement
People management
Supervision of two Bachelor students and two Master students.
Teaching
Institut National des Sciences Appliquées (INSA), Toulouse. Lab courses for 1st to 5th year students:
-
Solution Chemistry
-
Molecular biology
-
Microbiology
-
Biocatalysis
Projets
From 2019: Postdoctoral fellowship within the Partenarial Chair E2S UPPA – MANTA https://e2s-uppa.eu/en/research/chairs-of-excellence/manta-marine-materials.html
Funded by E2S UPPA, Communauté d’Agglomération Pays Basque, Région Nouvelle Aquitaine, Comité Interdépartemental des Pêches Maritimes et des Elevages Marins, Laboratoire de Biarritz and Lees for 5 years at UPPA, France