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PCM Seminar - Pr Peter CormackJeudi 16 janvier 2025, 15h00 - Amphi IPREM
Professor Peter Cormack
Department of Pure & Applied Chemistry, University of Strathclyde, Glasgow, Scotland
"Porous Organic Polymers for the Selective Capture of Molecular Targets"
Porous organic polymers are exploited in a broad range of specialist and everyday applications, including as polymer supports in solid-phase synthesis work and heterogeneous catalysis, as ion-exchange resins for water purification, as tissue engineering scaffolds and as functional materials in biological assays. Furthermore, they are highly attractive for use in a number of important chemical separation scenarios, including as high-performance sorbents and stationary phases in solid-phase extraction (SPE) and chromatographic separation technologies, respectively, spanning large-scale chemical separations and analytical-scale work (e.g., the monitoring of environmental pollutants and drug molecules).
At the University of Strathclyde in Glasgow we specialize in the design, synthesis and application of porous organic polymers, optimised to solve an array of real-world scientific problems, including challenging analytical chemistry problems (in fields of application such as environmental analysis, bioanalysis, food analysis, forensic toxicology and omics). In this lecture, I will outline how we control the physical format, porosity and chemical functionality of porous polymers tailored for high-performance chemical separation work, and explain how the polymers can be used as advanced sorbents in SPE. Typically, the polymers are synthesized by methods such as precipitation polymerization and suspension polymerization, and porosity is installed into the polymers though the use of porogenic agents and/or hypercrosslinking methodologies. Affinity and selectivity for molecular targets by the polymers is ensured through the incorporation of chemical motifs such as ion-exchange groups or molecular receptors installed through template-directed synthetic strategies such as molecular imprinting. The latter approach delivers antibody binding mimics that we apply to disease diagnosis, prognosis and management.
Peter Cormack is Professor of Polymer Chemistry and Head of Materials & Computational Chemistry at the University of Strathclyde in Glasgow, Scotland, UK. Peter has a built a global reputation as international leader in polymer science, and he is motivated by a desire to pursue useful polymer chemistry research which promises tangible, societal benefits. Peter’s research interests lie predominantly in the areas of synthetic polymer chemistry and materials science, with special emphasis on the design, synthesis and applications of functional organic polymers, including porous organic solids, polymeric synthetic receptors, polymer microspheres, chemical sensors and ion-exchange resins
